CoQ10 is a component of the mitochondria and plays a key role in the synthesis of ATP. B vitamins are important cofactors needed to fuel the Krebs cycle, while optimal serum levels of magnesium are associated with healthy mitochondrial metabolism and nutrient transport. Nicotinamide mononucleotide (NMN) is a unique form of vitamin B3 that gets converted into nicotinamide adenine dinucleotide (NAD+). NAD+ declines with age and plays an important role in energy production within the mitochondria and cellular repair. Preliminary research suggests NMN supports synthesis of NAD+ in tissues, supporting cellular function and longevity, energy metabolism, aerobic capacity and glucose homeostasis. Acetyl-l-carnitine provides carnitine to transport long chain fatty acids into the mitochondria for energy as well as an acetyl group for the synthesis of the Krebs cycle precursor acetyl-CoA. Highly pure creatine monohydrate helps enhance the production of the ATP by acting as a precursor. This formula provides antioxidant support with vitamins C and E, as well as resveratrol, alpha lipoic acid and N-acetyl-l-cysteine. Antioxidants neutralize the free radicals generated during energy production in the mitochondria. In a double-blind, placebo-controlled, crossover study, the combination of creatine, CoQ10 and alpha lipoic acid supported energy production and antioxidant status within the mitochondria.