The main hormone responsible for menopause is progesterone.

Progesterone is produced by the corpus luteum, the residual part of the ovulatory follicle in the ovary.
It is the precursor of many essential hormones, especially testosterone. DHEA (hormone) is mostly produced by the adrenal gland, a small gland above the kidney.
Adrenal fatigue can present with very low levels of DHEA.
Testosterone in varying amounts is a very important hormone for both men and women.
Even though this is a crucial hormone, therapies that rely only on this therapy fail to provide the benefits of our balanced replacement program.
Estrogen, which is helpful in small amounts, is a minor contributor to a balanced hormone replacement regimen.